Literature summary extracted from

Zigler, J.S.; Hodgkinson, C.A.; Wright, M.; Klise, A.; Sundin, O.; Broman, K.W.; Hejtmancik, F.; Huang, H.; Patek, B.; Sergeev, Y.; Hose, S.; Brayton, C.; Xaiodong, J.; Vasquez, D.; Maragakis, N.; Mori, S.; Goldman, D.; Hoke, A.; Sinha, D.
A spontaneous missense mutation in branched chain keto acid dehydrogenase kinase in the rat affects both the central and peripheral nervous systems (2016), PLoS ONE, 11, e0160447.

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
2.7.11.4	mitochondrion	-	Rattus norvegicus	5739	-

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
2.7.11.4	ATP + [branched-chain keto-acid dehydrogenase (acetyl-transferring)]	Rattus norvegicus	the enzyme phosphorylates Ser293 of the E1alpha subunit of branched-chain keto-acid dehydrogenase	ADP + [branched-chain keto-acid dehydrogenase (acetyl-transferring)] phosphate	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.7.11.4	Rattus norvegicus	Q00972	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.7.11.4	brain	-	Rattus norvegicus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.7.11.4	ATP + [branched-chain keto-acid dehydrogenase (acetyl-transferring)]	the enzyme phosphorylates Ser293 of the E1alpha subunit of branched-chain keto-acid dehydrogenase	Rattus norvegicus	ADP + [branched-chain keto-acid dehydrogenase (acetyl-transferring)] phosphate	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
2.7.11.4	BCKDK	-	Rattus norvegicus
2.7.11.4	branched chain keto acid dehydrogenase kinase	-	Rattus norvegicus
2.7.11.4	branched-chain alpha-keto dehydrogenase kinase	-	Rattus norvegicus

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Release 2023.1 (January 2023)